STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NKI9_GASACExcision repair cross-complementation group 4. (879 aa)    
Predicted Functional Partners:
G3NSL9_GASAC
Excision repair cross-complementation group 1.
   
 0.999
G3NY50_GASAC
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.990
G3Q417_GASAC
Xeroderma pigmentosum, complementation group A.
    
 0.989
G3Q4I3_GASAC
Uncharacterized protein.
  
 0.986
G3NVE5_GASAC
FA complementation group C.
   
 0.985
G3NR39_GASAC
FA complementation group F.
    
 0.984
G3NIF3_GASAC
FA complementation group B.
   
 0.983
G3PJG6_GASAC
FA complementation group L.
    
 0.983
G3PLP7_GASAC
RecQ mediated genome instability 2.
    
 0.979
G3Q4N8_GASAC
MUS81 structure-specific endonuclease subunit.
    
 0.979
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.