Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
G3NKK2_GASACSpastin; Belongs to the AAA ATPase family. (495 aa)    
Predicted Functional Partners:
G3PS32_GASAC
IST1 factor associated with ESCRT-III.
    
 0.985
G3QAG4_GASAC
Chromatin modifying protein 1B.
    
 
 0.956
G3PDL3_GASAC
Atlastin GTPase 1.
   
 
 0.930
G3PCS8_GASAC
Si:dkey-97o5.1.
   
 0.894
G3PK47_GASAC
UBX domain protein 7.
   
 0.891
G3NZZ7_GASAC
Receptor expression-enhancing protein.
   
 
 0.876
G3NRQ7_GASAC
NME/NM23 family member 8; Belongs to the NDK family.
  
 0.856
G3PF23_GASAC
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.824
G3P322_GASAC
WD repeat domain 90.
    
 
 0.806
G3Q1D0_GASAC
DUF4502 domain-containing protein.
    
 0.785
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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