Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NL56_GASACEndothelin converting enzyme 1. (770 aa)    
Predicted Functional Partners:
G3NPP9_GASAC
Endothelin converting enzyme-like 1.
    
   0.794
G3P5J3_GASAC
Angiotensinogen; Belongs to the serpin family.
    
 0.674
G3NSM1_GASAC
DEAH (Asp-Glu-Ala-His) box polypeptide 40.
    
   0.636
G3PBV6_GASAC
Stromal interaction molecule 1a.
      
 0.623
G3PQI4_GASAC
Endothelin converting enzyme 2a.
 
 
  
 0.598
G3PI00_GASAC
ShKT domain-containing protein; Belongs to the CRISP family.
  
  
 0.571
G3Q349_GASAC
Peptidylglycine alpha-amidating monooxygenase.
   
  
 0.569
G3PR30_GASAC
Uncharacterized protein.
    
   0.565
EDNRA
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.550
G3P5C3_GASAC
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
   0.549
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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