Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NL63_GASACSpire-type actin nucleation factor 1b. (730 aa)    
Predicted Functional Partners:
G3PNI1_GASAC
GRB2 related adaptor protein 2a.
   
 0.941
G3NUY1_GASAC
Growth factor receptor-bound protein 2b.
    
 0.910
G3N5Q3_GASAC
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 0.798
G3NLI8_GASAC
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 0.798
G3NF67_GASAC
Cytoplasmic protein.
    
 0.788
G3NHC0_GASAC
Cytoplasmic protein.
    
 0.788
G3NXV3_GASAC
Tyrosine-protein kinase.
   
 0.785
G3Q450_GASAC
Tyrosine-protein kinase.
   
 0.785
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.742
G3P6Y7_GASAC
FH2 domain-containing protein.
    
 0.742
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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