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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NL70_GASACCyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (471 aa)    
Predicted Functional Partners:
G3NMD5_GASAC
Mitogen-activated protein kinase.
    
 0.941
G3Q5V7_GASAC
Mitogen-activated protein kinase.
    
 0.941
G3PJF7_GASAC
Mitogen-activated protein kinase.
    
 0.940
G3Q5W0_GASAC
Mitogen-activated protein kinase.
    
 0.940
G3NW10_GASAC
Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.
    
0.920
G3NZU1_GASAC
Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.
    
0.920
G3NHZ9_GASAC
Mitogen-activated protein kinase.
    
 0.919
G3NXY6_GASAC
Mitogen-activated protein kinase.
    
 0.919
G3NZN5_GASAC
Mitogen-activated protein kinase.
    
 0.919
G3PNU7_GASAC
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.914
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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