Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TUT7Terminal uridylyl transferase 7. (1051 aa)    
Predicted Functional Partners:
dis3l2
DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
   
 
 0.922
LIN28A
Lin-28 homolog A.
    
 0.891
G3NE18_GASAC
Poly(A) polymerase gamma.
   
 
 0.712
G3NE21_GASAC
Uncharacterized protein.
   
 
 0.712
G3NS21_GASAC
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
 
 0.712
G3NE42_GASAC
Symplekin.
   
 0.679
G3P0K7_GASAC
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.677
G3PWU6_GASAC
Terminal nucleotidyltransferase 4B.
      
 0.669
G3Q0Y4_GASAC
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
  0.649
G3QCC5_GASAC
B-cell translocation gene 4.
      
 0.635
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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