Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NLT1_GASACBHLH domain-containing protein. (199 aa)    
Predicted Functional Partners:
G3NW90_GASAC
Retinol binding protein 7a, cellular.
    
   0.751
G3PS19_GASAC
Nicotinamide-nucleotide adenylyltransferase.
    
   0.751
G3P574_GASAC
V-rel avian reticuloendotheliosis viral oncogene homolog B.
    
 
 0.730
G3Q9A6_GASAC
V-rel avian reticuloendotheliosis viral oncogene homolog A.
    
 
 0.730
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.679
G3Q1D2_GASAC
F-box and WD repeat domain containing 11a.
    
 
 0.614
TCF4
Transcription factor 4.
    
 
 0.583
G3NRW4_GASAC
BHLH domain-containing protein.
    
 
 0.583
G3PGW1_GASAC
Transcription factor 3b.
    
 
 0.583
G3PRC8_GASAC
Transcription factor 3a.
    
 
 0.583
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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