G3NLW6_GASAC protein (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	EIF3B	ENSGACP00000008154	ENSGACP00000022112	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.597
EIF2AK4	G3NK72_GASAC	ENSGACP00000008154	ENSGACP00000005734	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 2.	0.612
EIF2AK4	G3NK90_GASAC	ENSGACP00000008154	ENSGACP00000005752	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 2.	0.612
EIF2AK4	G3NLW6_GASAC	ENSGACP00000008154	ENSGACP00000006329	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	0.945
EIF2AK4	G3P1A2_GASAC	ENSGACP00000008154	ENSGACP00000011375	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.999
EIF2AK4	G3PGS3_GASAC	ENSGACP00000008154	ENSGACP00000016798	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.962
EIF2AK4	G3PJC8_GASAC	ENSGACP00000008154	ENSGACP00000017707	Eukaryotic translation initiation factor 2 alpha kinase 4.	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.	0.537
EIF2AK4	G3PMT1_GASAC	ENSGACP00000008154	ENSGACP00000018914	Eukaryotic translation initiation factor 2 alpha kinase 4.	5'-3' exoribonuclease 1.	0.470
EIF3B	EIF2AK4	ENSGACP00000022112	ENSGACP00000008154	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.597
EIF3B	G3NLW6_GASAC	ENSGACP00000022112	ENSGACP00000006329	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	0.913
EIF3B	G3P1A2_GASAC	ENSGACP00000022112	ENSGACP00000011375	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.997
EIF3B	G3P5K4_GASAC	ENSGACP00000022112	ENSGACP00000012877	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	RIO kinase 2 (yeast).	0.418
EIF3B	G3PDV0_GASAC	ENSGACP00000022112	ENSGACP00000015774	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.990
EIF3B	G3PGS3_GASAC	ENSGACP00000022112	ENSGACP00000016798	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.996
EIF3B	G3PJC8_GASAC	ENSGACP00000022112	ENSGACP00000017707	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.	0.987
EIF3B	G3PMT1_GASAC	ENSGACP00000022112	ENSGACP00000018914	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	5'-3' exoribonuclease 1.	0.405
G3NK72_GASAC	EIF2AK4	ENSGACP00000005734	ENSGACP00000008154	Eukaryotic translation initiation factor 2-alpha kinase 2.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.612
G3NK72_GASAC	G3NLW6_GASAC	ENSGACP00000005734	ENSGACP00000006329	Eukaryotic translation initiation factor 2-alpha kinase 2.	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	0.930
G3NK72_GASAC	G3P1A2_GASAC	ENSGACP00000005734	ENSGACP00000011375	Eukaryotic translation initiation factor 2-alpha kinase 2.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.998
G3NK72_GASAC	G3PGS3_GASAC	ENSGACP00000005734	ENSGACP00000016798	Eukaryotic translation initiation factor 2-alpha kinase 2.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.628