Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NLY4_GASACPeptidylprolyl isomerase. (576 aa)    
Predicted Functional Partners:
G3Q265_GASAC
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
    
 
 0.840
G3NEW8_GASAC
Nuclear receptor subfamily 2, group C, member 2.
    
 0.773
G3P769_GASAC
Nuclear receptor subfamily 2, group C, member 1.
    
 0.773
G3NZ66_GASAC
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.731
G3P2F4_GASAC
Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.731
G3PBZ3_GASAC
Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.
  
 
 0.727
G3P519_GASAC
INO80 complex subunit E.
    
 
 0.707
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
      
 0.680
G3NKU1_GASAC
Deoxythymidylate kinase (thymidylate kinase).
      
 0.678
G3NPL5_GASAC
Secreted frizzled-related protein 1a.
   
  
 0.675
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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