STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NM42_GASACE1A binding protein p300 a. (2344 aa)    
Predicted Functional Partners:
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.991
G3Q4J0_GASAC
CREB binding protein a.
  
0.986
G3NU10_GASAC
Sp1 transcription factor.
   
 0.985
G3PBM0_GASAC
CREB binding protein b.
  
0.985
G3NRM5_GASAC
Catenin (cadherin-associated protein), beta 1.
    
 0.982
G3NYV6_GASAC
Interferon regulatory factor 3.
    
 0.982
G3N9I3_GASAC
Myb-like, SWIRM and MPN domains 1.
   
 
 0.978
G3NMN1_GASAC
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.964
G3NYD5_GASAC
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a.
    
 0.957
G3PXI1_GASAC
Mastermind-like transcriptional coactivator 1.
   
 0.955
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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