Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IWS1Interacts with SUPT6H, CTD assembly factor 1. (358 aa)    
Predicted Functional Partners:
G3QB56_GASAC
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.999
G3PQA7_GASAC
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.985
G3Q0Y4_GASAC
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.985
G3PSY3_GASAC
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.979
G3Q530_GASAC
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.978
G3NMH3_GASAC
Transcription elongation factor SPT5.
   
 0.976
G3NC28_GASAC
Polymerase (RNA) II (DNA directed) polypeptide C.
    
 0.974
G3QA22_GASAC
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.973
G3P1H7_GASAC
WW domain-containing protein.
   
 
 0.967
G3Q6T9_GASAC
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.965
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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