STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IWS1Interacts with SUPT6H, CTD assembly factor 1. (358 aa)    
Predicted Functional Partners:
G3QB56_GASAC
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.999
G3NMH3_GASAC
Transcription elongation factor SPT5.
   
 0.980
G3Q0Y4_GASAC
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.980
G3Q530_GASAC
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.978
G3NZF0_GASAC
Endonuclease/exonuclease/phosphatase family domain containing 1.
   
 0.974
SRBD1
S1 RNA binding domain 1.
   
 0.974
G3Q6T9_GASAC
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.971
G3NC28_GASAC
Polymerase (RNA) II (DNA directed) polypeptide C.
   
 0.968
G3PQA7_GASAC
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.966
G3PSY3_GASAC
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.962
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.