Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (149 aa)    
Predicted Functional Partners:
G3PA33_GASAC
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.999
G3Q9D2_GASAC
Small nuclear ribonucleoprotein polypeptide F.
   
 0.999
G3NU46_GASAC
Small nuclear ribonucleoprotein Sm D2.
   
 0.998
G3PIM5_GASAC
Small nuclear ribonucleoprotein polypeptide G.
   
 0.998
G3PZX4_GASAC
Small nuclear ribonucleoprotein Sm D3.
   
 0.998
G3NG36_GASAC
Small nuclear ribonucleoprotein-associated protein.
   
 0.996
SNRPD1
Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.
   
 0.995
G3N5K7_GASAC
Small nuclear ribonucleoprotein 70 (U1).
   
 0.992
G3P5Y3_GASAC
Small nuclear ribonucleoprotein polypeptide A.
   
 0.988
G3Q7Z9_GASAC
Small nuclear ribonucleoprotein polypeptide B2.
   
 0.988
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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