Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMCO4Single-pass membrane protein with coiled-coil domains 4. (59 aa)    
Predicted Functional Partners:
G3PIQ4_GASAC
Uncharacterized protein.
      
 0.838
G3PYF5_GASAC
PDZ domain containing 11.
      
 0.672
G3QBI8_GASAC
Hephaestin-like 1b; Belongs to the multicopper oxidase family.
      
 0.649
G3QA68_GASAC
Zgc:85789.
      
 0.628
G3Q6E0_GASAC
Transmembrane 4 L six family member 5.
      
 0.624
G3PWU4_GASAC
Nudix (nucleoside diphosphate linked moiety X)-type motif 6.
      
 0.601
MED17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.552
G3P706_GASAC
Coagulation factor II (thrombin) receptor-like 2.
      
 0.474
F2RL2
Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.474
G3NSL4_GASAC
Ceruloplasmin; Belongs to the multicopper oxidase family.
      
 0.450
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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