Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMAD3Mothers against decapentaplegic homolog. (426 aa)    
Predicted Functional Partners:
G3N5X0_GASAC
Mothers against decapentaplegic homolog.
   
0.985
G3NX80_GASAC
Mothers against decapentaplegic homolog.
   
0.985
SMAD4
Mothers against decapentaplegic homolog.
   
0.985
G3PWB9_GASAC
Zinc finger, FYVE domain containing 9a.
   
 0.980
G3Q6G7_GASAC
LEM domain containing 3.
    
 0.979
TGFBR2
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.978
G3NI05_GASAC
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.976
G3N6K6_GASAC
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.974
G3N7H2_GASAC
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.974
ACVR1C
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.974
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: medium (46%) [HD]