Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
G3NN79_GASACProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (535 aa)    
Predicted Functional Partners:
G3P0L0_GASAC
Surfactant protein Bb.
     
 
0.900
G3PI40_GASAC
Galactosylceramidase b.
    
 
 0.900
G3PYH7_GASAC
Uncharacterized protein.
     
 
0.900
G3PDK2_GASAC
Glucosylceramidase.
   
 0.867
G3PJC0_GASAC
Alpha-galactosidase.
   
 0.846
G3PLZ3_GASAC
Alpha-galactosidase.
   
 0.846
G3PZQ4_GASAC
Alpha-galactosidase.
   
 0.846
G3PFR8_GASAC
Arylsulfatase A.
     
 0.839
G3NDR8_GASAC
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
   
 
 0.821
G3PVF1_GASAC
GM2 ganglioside activator.
   
 
 0.798
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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