G3NUR3_GASAC protein (Gasterosteus aculeatus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

G3NUR3_GASAC

Ubiquitin carboxyl-terminal hydrolase. (781 aa)

Predicted Functional Partners:

G3PGJ1_GASAC

0.998

G3N781_GASAC

0.990

G3PCM8_GASAC

0.985

G3QA52_GASAC

0.963

G3NZ68_GASAC

0.960

G3PCG6_GASAC

0.959

G3NQJ7_GASAC

0.952

G3PJG6_GASAC

0.921

G3P8Y0_GASAC

0.865

G3PHC8_GASAC

0.865

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N781_GASAC	G3NQJ7_GASAC	ENSGACP00000001158	ENSGACP00000007613	FA complementation group D2.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.404
G3N781_GASAC	G3NUR3_GASAC	ENSGACP00000001158	ENSGACP00000009082	FA complementation group D2.	Ubiquitin carboxyl-terminal hydrolase.	0.990
G3N781_GASAC	G3NZ68_GASAC	ENSGACP00000001158	ENSGACP00000010640	FA complementation group D2.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.955
G3N781_GASAC	G3PCG6_GASAC	ENSGACP00000001158	ENSGACP00000015290	FA complementation group D2.	Ribosomal protein S27a.	0.973
G3N781_GASAC	G3PCM8_GASAC	ENSGACP00000001158	ENSGACP00000015352	FA complementation group D2.	FA complementation group I.	0.999
G3N781_GASAC	G3PGJ1_GASAC	ENSGACP00000001158	ENSGACP00000016715	FA complementation group D2.	WD repeat domain 48b.	0.945
G3N781_GASAC	G3PJG6_GASAC	ENSGACP00000001158	ENSGACP00000017746	FA complementation group D2.	FA complementation group L.	0.996
G3N781_GASAC	G3QA52_GASAC	ENSGACP00000001158	ENSGACP00000026768	FA complementation group D2.	Ubiquitin B.	0.973
G3NQJ7_GASAC	G3N781_GASAC	ENSGACP00000007613	ENSGACP00000001158	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	FA complementation group D2.	0.404
G3NQJ7_GASAC	G3NUR3_GASAC	ENSGACP00000007613	ENSGACP00000009082	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin carboxyl-terminal hydrolase.	0.952
G3NQJ7_GASAC	G3NZ68_GASAC	ENSGACP00000007613	ENSGACP00000010640	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.976
G3NQJ7_GASAC	G3PCG6_GASAC	ENSGACP00000007613	ENSGACP00000015290	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ribosomal protein S27a.	0.979
G3NQJ7_GASAC	G3PGJ1_GASAC	ENSGACP00000007613	ENSGACP00000016715	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	WD repeat domain 48b.	0.762
G3NQJ7_GASAC	G3PJG6_GASAC	ENSGACP00000007613	ENSGACP00000017746	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	FA complementation group L.	0.420
G3NQJ7_GASAC	G3QA52_GASAC	ENSGACP00000007613	ENSGACP00000026768	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin B.	0.972
G3NUR3_GASAC	G3N781_GASAC	ENSGACP00000009082	ENSGACP00000001158	Ubiquitin carboxyl-terminal hydrolase.	FA complementation group D2.	0.990
G3NUR3_GASAC	G3NQJ7_GASAC	ENSGACP00000009082	ENSGACP00000007613	Ubiquitin carboxyl-terminal hydrolase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.952
G3NUR3_GASAC	G3NZ68_GASAC	ENSGACP00000009082	ENSGACP00000010640	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.960
G3NUR3_GASAC	G3P8Y0_GASAC	ENSGACP00000009082	ENSGACP00000014054	Ubiquitin carboxyl-terminal hydrolase.	WD repeat domain 20a.	0.865
G3NUR3_GASAC	G3PCG6_GASAC	ENSGACP00000009082	ENSGACP00000015290	Ubiquitin carboxyl-terminal hydrolase.	Ribosomal protein S27a.	0.959

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Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.719

expected number of edges:

26

PPI enrichment p-value:

0.521

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140647

P450-containing electron transport chain

2 of 2

3.28

1.33

0.0040

GO:0006091

Generation of precursor metabolites and energy

5 of 283

1.53

1.31

0.00094

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009055

Electron transfer activity

4 of 66

2.06

2.01

9.76e-05

GO:0051536

Iron-sulfur cluster binding

4 of 79

1.99

1.97

9.76e-05

GO:0016651

Oxidoreductase activity, acting on NAD(P)H

3 of 58

1.99

1.38

0.0020

GO:0016491

Oxidoreductase activity

6 of 793

1.16

1.02

0.00078

GO:0004312

Fatty acid synthase activity

2 of 19

2.3

0.92

0.0198

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005739

Mitochondrion

6 of 1409

0.91

0.5

0.0399

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:23332

Mixed, incl. Retinol metabolism, and Valine, leucine and isoleucine degradation

4 of 181

1.63

1.01

0.0080

CL:23532

Mixed, incl. Beta-ketoacyl synthase, C-terminal domain, and Acyl transferase domain

2 of 6

2.8

1.01

0.0152

CL:23336

Mixed, incl. Valine, leucine and isoleucine degradation, and Fatty acid biosynthesis

3 of 133

1.63

0.68

0.0460

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

4 of 200

1.58

1.53

0.00026

map00061

Fatty acid biosynthesis

2 of 32

2.08

1.08

0.0090

map00860

Porphyrin and chlorophyll metabolism

2 of 85

1.65

0.69

0.0444

map01212

Fatty acid metabolism

2 of 93

1.61

0.68

0.0444

map01100

Metabolic pathways

9 of 3033

0.75

0.65

0.00022

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-2395516

Electron transport from NADPH to Ferredoxin

2 of 4

2.98

1.22

0.0062

MAP-196108

Pregnenolone biosynthesis

2 of 13

2.47

0.91

0.0217

MAP-1362409

Mitochondrial iron-sulfur cluster biogenesis

2 of 16

2.38

0.91

0.0217

MAP-211945

Phase I - Functionalization of compounds

3 of 125

1.66

0.83

0.0217

MAP-211976

Endogenous sterols

2 of 36

2.03

0.73

0.0443

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005739

Mitochondrion

6 of 892

1.11

0.84

0.0035

GOCC:0005747

Mitochondrial respiratory chain complex I

2 of 26

2.17

0.72

0.0475

GOCC:0005737

Cytoplasm

10 of 6155

0.49

0.33

0.0290

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00037

4Fe-4S binding domain

2 of 3

3.1

1.25

0.0057

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR010226

NADH-quinone oxidoreductase, chain I

2 of 2

3.28

1.11

0.0101

IPR001055

Adrenodoxin

2 of 2

3.28

1.11

0.0101

IPR017900

4Fe-4S ferredoxin, iron-sulphur binding, conserved site

2 of 6

2.8

1.0

0.0157

IPR036010

2Fe-2S ferredoxin-like superfamily

2 of 8

2.68

0.95

0.0190

IPR017896

4Fe-4S ferredoxin-type, iron-sulphur binding domain

2 of 10

2.58

0.91

0.0222

(more ...)

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