STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCH1Patched 1. (1032 aa)    
Predicted Functional Partners:
G3Q821_GASAC
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.983
G3NIG1_GASAC
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.975
G3P2Y8_GASAC
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.972
G3NST5_GASAC
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.964
G3PSE1_GASAC
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.964
G3PF72_GASAC
Cell adhesion associated, oncogene regulated.
    
 0.941
SMURF2
E3 ubiquitin-protein ligase.
   
 0.869
G3NVD5_GASAC
E3 ubiquitin-protein ligase.
    
 0.868
SMURF1
E3 ubiquitin-protein ligase.
    
 0.868
G3PKV6_GASAC
Patched 2.
  
 
 
0.849
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.