STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NYY3_GASACHistone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (938 aa)    
Predicted Functional Partners:
G3NIY0_GASAC
AT rich interactive domain 4A (RBP1-like).
    
 0.947
G3NK22_GASAC
Translocase of outer mitochondrial membrane 20.
    
 0.947
G3PNT4_GASAC
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
   
 0.893
G3NWY1_GASAC
SIN3 transcription regulator family member Aa.
    
 0.828
G3P9I8_GASAC
SIN3 transcription regulator family member B.
    
 0.828
G3PYS7_GASAC
HDAC_interact domain-containing protein.
    
 0.828
RANBP2
RAN binding protein 2.
  
 0.813
G3NZ68_GASAC
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.802
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.799
RBBP4-2
RB binding protein 4, chromatin remodeling factor.
   
 0.799
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.