STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3PDG0_GASACL-2-hydroxyglutarate dehydrogenase. (444 aa)    
Predicted Functional Partners:
G3P9W8_GASAC
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.971
G3Q7Q6_GASAC
Malate synthase-like.
  
 
 0.948
G3NQT9_GASAC
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 
 0.941
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 
 0.940
G3PQ54_GASAC
Glycerol-3-phosphate dehydrogenase 2 (mitochondrial).
    
 0.935
G3Q870_GASAC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.931
G3N529_GASAC
Uncharacterized protein.
    
 0.923
G3PBU7_GASAC
Fumarate hydratase.
    
 0.923
G3QB01_GASAC
Argininosuccinate lyase.
  
 
 0.913
G3N8S9_GASAC
Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.911
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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