node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | G3N4S4_GASAC | ENSGACP00000002941 | ENSGACP00000000294 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.586 |
FEN1 | G3N741_GASAC | ENSGACP00000002941 | ENSGACP00000001117 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.586 |
FEN1 | G3ND45_GASAC | ENSGACP00000002941 | ENSGACP00000003245 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.604 |
FEN1 | G3NQD4_GASAC | ENSGACP00000002941 | ENSGACP00000007550 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Xeroderma pigmentosum, complementation group C. | 0.711 |
FEN1 | G3NS32_GASAC | ENSGACP00000002941 | ENSGACP00000008149 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.717 |
FEN1 | G3NZM3_GASAC | ENSGACP00000002941 | ENSGACP00000010796 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly (ADP-ribose) glycohydrolase a. | 0.586 |
FEN1 | G3PC75_GASAC | ENSGACP00000002941 | ENSGACP00000015199 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Tower domain-containing protein. | 0.738 |
FEN1 | G3PQK4_GASAC | ENSGACP00000002941 | ENSGACP00000019889 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Von Willebrand factor A domain containing 5B2. | 0.691 |
FEN1 | G3PT40_GASAC | ENSGACP00000002941 | ENSGACP00000020776 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Zgc:110269. | 0.850 |
G3N4S4_GASAC | FEN1 | ENSGACP00000000294 | ENSGACP00000002941 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.586 |
G3N4S4_GASAC | G3N741_GASAC | ENSGACP00000000294 | ENSGACP00000001117 | Uncharacterized protein. | Uncharacterized protein. | 0.902 |
G3N4S4_GASAC | G3PQK4_GASAC | ENSGACP00000000294 | ENSGACP00000019889 | Uncharacterized protein. | Von Willebrand factor A domain containing 5B2. | 0.776 |
G3N4S4_GASAC | G3PT40_GASAC | ENSGACP00000000294 | ENSGACP00000020776 | Uncharacterized protein. | Zgc:110269. | 0.588 |
G3N741_GASAC | FEN1 | ENSGACP00000001117 | ENSGACP00000002941 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.586 |
G3N741_GASAC | G3N4S4_GASAC | ENSGACP00000001117 | ENSGACP00000000294 | Uncharacterized protein. | Uncharacterized protein. | 0.902 |
G3N741_GASAC | G3PQK4_GASAC | ENSGACP00000001117 | ENSGACP00000019889 | Uncharacterized protein. | Von Willebrand factor A domain containing 5B2. | 0.776 |
G3N741_GASAC | G3PT40_GASAC | ENSGACP00000001117 | ENSGACP00000020776 | Uncharacterized protein. | Zgc:110269. | 0.597 |
G3ND45_GASAC | FEN1 | ENSGACP00000003245 | ENSGACP00000002941 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.604 |
G3ND45_GASAC | G3PQK4_GASAC | ENSGACP00000003245 | ENSGACP00000019889 | Uncharacterized protein. | Von Willebrand factor A domain containing 5B2. | 0.776 |
G3ND45_GASAC | G3PT40_GASAC | ENSGACP00000003245 | ENSGACP00000020776 | Uncharacterized protein. | Zgc:110269. | 0.586 |