STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3PUG5_GASACCell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa)    
Predicted Functional Partners:
G3PQA7_GASAC
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.999
G3PSY3_GASAC
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.990
G3P9Q5_GASAC
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.989
G3Q530_GASAC
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.989
G3NWS8_GASAC
WD repeat domain 61.
    
 0.982
G3Q0Y4_GASAC
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.980
G3PEW6_GASAC
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.978
G3NKA0_GASAC
Cyclin-dependent kinase 2 interacting protein.
   
 0.963
G3Q6T9_GASAC
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.961
G3NMH3_GASAC
Transcription elongation factor SPT5.
    
 0.960
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.