STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3Q366_GASACDerlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)    
Predicted Functional Partners:
G3NQ33_GASAC
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
0.980
G3PI80_GASAC
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 0.971
G3Q4E9_GASAC
Synovial apoptosis inhibitor 1, synoviolin.
   
 0.965
G3PBU4_GASAC
Si:dkey-24p1.6.
   
 0.960
G3N6J5_GASAC
OS9 endoplasmic reticulum lectin.
    
 0.958
G3NQ70_GASAC
Endoplasmic reticulum lectin 1.
    
 0.958
G3PVF0_GASAC
Autocrine motility factor receptor b.
   
 0.957
G3NIR4_GASAC
Ubiquitin recognition factor in ER associated degradation 1.
   
 
 0.948
G3P597_GASAC
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.921
G3Q4U8_GASAC
Zgc:136908; Belongs to the AAA ATPase family.
   
 0.921
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.