STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3Q7H8_GASACPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (486 aa)    
Predicted Functional Partners:
G3QA92_GASAC
Estrogen-related receptor alpha.
   
 0.991
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
   
 0.982
PPARA
Peroxisome proliferator-activated receptor alpha b.
   
 0.982
G3Q5B0_GASAC
Peroxisome proliferator-activated receptor alpha a.
   
 0.972
G3NGK0_GASAC
Uncharacterized protein.
    
 0.963
G3NY67_GASAC
BUD31 homolog.
   
 0.961
G3PDK1_GASAC
Crooked neck pre-mRNA splicing factor 1.
   
 0.959
G3NP39_GASAC
SNW domain containing 1.
   
 0.958
G3P6H9_GASAC
XPA binding protein 2.
   
 0.957
G3NGE9_GASAC
ISY1 splicing factor homolog.
   
 0.956
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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