APLF protein (Gasterosteus aculeatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

APLF

Aprataxin and PNKP like factor. (482 aa)

Predicted Functional Partners:

G3PG11_GASAC

0.991

G3QCE5_GASAC

0.991

G3NM92_GASAC

0.989

G3PBI6_GASAC

0.989

G3PM28_GASAC

0.989

G3Q0X1_GASAC

0.988

G3NS32_GASAC

0.985

G3PPN5_GASAC

0.985

G3NJ88_GASAC

0.979

G3PLQ5_GASAC

0.978

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLF	G3NJ88_GASAC	ENSGACP00000026005	ENSGACP00000005399	Aprataxin and PNKP like factor.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.979
APLF	G3NM92_GASAC	ENSGACP00000026005	ENSGACP00000006455	Aprataxin and PNKP like factor.	X-ray repair complementing defective repair in Chinese hamster cells 6.	0.989
APLF	G3NS32_GASAC	ENSGACP00000026005	ENSGACP00000008149	Aprataxin and PNKP like factor.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.985
APLF	G3PBI6_GASAC	ENSGACP00000026005	ENSGACP00000014960	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.989
APLF	G3PG11_GASAC	ENSGACP00000026005	ENSGACP00000016535	Aprataxin and PNKP like factor.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.991
APLF	G3PLQ5_GASAC	ENSGACP00000026005	ENSGACP00000018536	Aprataxin and PNKP like factor.	Chromodomain helicase DNA binding protein 1-like.	0.978
APLF	G3PM28_GASAC	ENSGACP00000026005	ENSGACP00000018659	Aprataxin and PNKP like factor.	DNA ligase.	0.989
APLF	G3PPN5_GASAC	ENSGACP00000026005	ENSGACP00000019570	Aprataxin and PNKP like factor.	Tyrosyl-DNA phosphodiesterase 1.	0.985
APLF	G3Q0X1_GASAC	ENSGACP00000026005	ENSGACP00000023516	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase.	0.988
APLF	G3QCE5_GASAC	ENSGACP00000026005	ENSGACP00000027561	Aprataxin and PNKP like factor.	DNA ligase.	0.991
G3NJ88_GASAC	APLF	ENSGACP00000005399	ENSGACP00000026005	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Aprataxin and PNKP like factor.	0.979
G3NJ88_GASAC	G3NM92_GASAC	ENSGACP00000005399	ENSGACP00000006455	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	X-ray repair complementing defective repair in Chinese hamster cells 6.	0.941
G3NJ88_GASAC	G3NS32_GASAC	ENSGACP00000005399	ENSGACP00000008149	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.910
G3NJ88_GASAC	G3PBI6_GASAC	ENSGACP00000005399	ENSGACP00000014960	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.995
G3NJ88_GASAC	G3PG11_GASAC	ENSGACP00000005399	ENSGACP00000016535	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.998
G3NJ88_GASAC	G3PM28_GASAC	ENSGACP00000005399	ENSGACP00000018659	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA ligase.	0.910
G3NJ88_GASAC	G3PPN5_GASAC	ENSGACP00000005399	ENSGACP00000019570	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Tyrosyl-DNA phosphodiesterase 1.	0.988
G3NJ88_GASAC	G3Q0X1_GASAC	ENSGACP00000005399	ENSGACP00000023516	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Poly [ADP-ribose] polymerase.	0.982
G3NJ88_GASAC	G3QCE5_GASAC	ENSGACP00000005399	ENSGACP00000027561	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA ligase.	0.998
G3NM92_GASAC	APLF	ENSGACP00000006455	ENSGACP00000026005	X-ray repair complementing defective repair in Chinese hamster cells 6.	Aprataxin and PNKP like factor.	0.989