STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBNAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. (245 aa)    
Predicted Functional Partners:
KOO02691.1
Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.819
KOO05281.1
DNA transformation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.796
KOO01796.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.791
KOO03312.1
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadD family.
   
 0.772
KOO04401.1
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.756
KOO03690.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.751
KOO05488.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.743
KOO04685.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.743
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 0.743
KOO03048.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.730
Your Current Organism:
Vibrio nereis
NCBI taxonomy Id: 693
Other names: ATCC 25917, Beneckea nereida, Beneckea nereis, CAIM 322, CCUG 28585, CIP 103194, DSM 19584, IFO 15637, JCM 21190, LMG 3895, LMG:3895, NBRC 15637, NCCB 73020, V. nereis, strain 80
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.