STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOO02955.1Coproporphyrinogen III oxidase; Catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (462 aa)    
Predicted Functional Partners:
KOO03301.1
Hypothetical protein; Receptor for colicin S4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.871
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.865
KOO03419.1
Cytochrome C oxidase Cbb3; CcoN; FixN; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.829
KOO03420.1
Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.789
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.776
KOO04934.1
4Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.768
KOO05145.1
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
0.703
KOO04875.1
Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.692
KOO03422.1
Cytochrome C oxidase Cbb3; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
  
 0.678
KOO03532.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.590
Your Current Organism:
Vibrio nereis
NCBI taxonomy Id: 693
Other names: ATCC 25917, Beneckea nereida, Beneckea nereis, CAIM 322, CCUG 28585, CIP 103194, DSM 19584, IFO 15637, JCM 21190, LMG 3895, LMG:3895, NBRC 15637, NCCB 73020, V. nereis, strain 80
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