STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
envZOsmolarity sensor protein; Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)    
Predicted Functional Partners:
ompR
Osmolarity response regulator; Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
KOO02417.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.981
KOO02368.1
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.943
KOO04560.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.935
KOO05327.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.903
KOO05284.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.888
KOO05248.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.887
KOO02385.1
TorR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.876
KOO02627.1
Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.868
KOO03198.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.860
Your Current Organism:
Vibrio nereis
NCBI taxonomy Id: 693
Other names: ATCC 25917, Beneckea nereida, Beneckea nereis, CAIM 322, CCUG 28585, CIP 103194, DSM 19584, IFO 15637, JCM 21190, LMG 3895, LMG:3895, NBRC 15637, NCCB 73020, V. nereis, strain 80
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.