STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM26965.1Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)    
Predicted Functional Partners:
SHL16444.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.968
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.941
SHM43224.1
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.923
SHM27777.1
Glutamate synthase (NADH) large subunit.
    
 0.918
SHL18551.1
Glycine dehydrogenase; Belongs to the GcvP family.
   
  
 0.917
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.910
SHL96656.1
Aconitase.
  
 
 0.901
SHL08060.1
Aconitase.
  
 0.871
SHL96620.1
Aconitase.
  
 0.871
SHL68276.1
Succinate dehydrogenase subunit A.
  
 
 0.790
Your Current Organism:
Flavobacterium xanthum
NCBI taxonomy Id: 69322
Other names: ACAM 81, Cytophaga xantha, DSM 3661, F. xanthum, IFO 14972, JCM 20358, LMG 8372, LMG:8372, NBRC 14972, NCIMB 2069
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.