THI1 protein (Chara braunii) - STRING interaction network

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THI1

Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...] (371 aa)

Predicted Functional Partners:

CBR_g6345

0.801

CBR_g30996

0.795

CBR_g6347

0.762

CBR_g64517

0.762

CBR_g22296

0.733

CBR_g39648

0.699

CBR_g61469

0.699

CBR_g3113

0.699

CBR_g3802

0.699

CBR_g3800

0.699

Your Current Organism:

Chara braunii

NCBI taxonomy Id: 69332
Other names: C. braunii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR_g22296	CBR_g6345	A0A388L2R5	A0A388KJR9	PfkB domain-containing protein.	TMP-TENI domain-containing protein.	0.722
CBR_g22296	CBR_g6347	A0A388L2R5	A0A388KJH8	PfkB domain-containing protein.	Uncharacterized protein.	0.722
CBR_g22296	CBR_g64517	A0A388L2R5	A0A388MFQ6	PfkB domain-containing protein.	Uncharacterized protein.	0.722
CBR_g22296	THI1	A0A388L2R5	A0A388JXH1	PfkB domain-containing protein.	Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]	0.733
CBR_g30996	CBR_g6345	A0A388LE07	A0A388KJR9	Uncharacterized protein.	TMP-TENI domain-containing protein.	0.980
CBR_g30996	CBR_g6347	A0A388LE07	A0A388KJH8	Uncharacterized protein.	Uncharacterized protein.	0.966
CBR_g30996	CBR_g64517	A0A388LE07	A0A388MFQ6	Uncharacterized protein.	Uncharacterized protein.	0.966
CBR_g30996	THI1	A0A388LE07	A0A388JXH1	Uncharacterized protein.	Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]	0.795
CBR_g3113	CBR_g6345	A0A388KET7	A0A388KJR9	PfkB domain-containing protein.	TMP-TENI domain-containing protein.	0.722
CBR_g3113	CBR_g6347	A0A388KET7	A0A388KJH8	PfkB domain-containing protein.	Uncharacterized protein.	0.722
CBR_g3113	CBR_g64517	A0A388KET7	A0A388MFQ6	PfkB domain-containing protein.	Uncharacterized protein.	0.722
CBR_g3113	THI1	A0A388KET7	A0A388JXH1	PfkB domain-containing protein.	Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]	0.699
CBR_g3800	CBR_g6345	A0A388KGC1	A0A388KJR9	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	TMP-TENI domain-containing protein.	0.722
CBR_g3800	CBR_g6347	A0A388KGC1	A0A388KJH8	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	Uncharacterized protein.	0.722
CBR_g3800	CBR_g64517	A0A388KGC1	A0A388MFQ6	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	Uncharacterized protein.	0.722
CBR_g3800	THI1	A0A388KGC1	A0A388JXH1	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]	0.699
CBR_g3802	CBR_g6345	A0A388KGA9	A0A388KJR9	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	TMP-TENI domain-containing protein.	0.722
CBR_g3802	CBR_g6347	A0A388KGA9	A0A388KJH8	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	Uncharacterized protein.	0.722
CBR_g3802	CBR_g64517	A0A388KGA9	A0A388MFQ6	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	Uncharacterized protein.	0.722
CBR_g3802	THI1	A0A388KGA9	A0A388JXH1	PfkB domain-containing protein; Belongs to the carbohydrate kinase PfkB family.	Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]	0.699

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