CBR_g19121 protein (Chara braunii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

CBR_g19121

Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1330 aa)

Predicted Functional Partners:

CBR_g50831

0.905

CBR_g18972

0.820

CBR_g8649

0.813

CBR_g12706

0.813

CBR_g32516

0.813

CBR_g50450

0.813

CBR_g32190

0.811

CBR_g5607

0.797

CBR_g74496

0.791

CBR_g5686

0.791

Your Current Organism:

Chara braunii

NCBI taxonomy Id: 69332
Other names: C. braunii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR_g12706	CBR_g19121	A0A388KSG5	A0A388KXE6	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.813
CBR_g12706	CBR_g5686	A0A388KSG5	A0A388JRW0	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.407
CBR_g12706	CBR_g74496	A0A388KSG5	A0A388JJB3	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.407
CBR_g18972	CBR_g19121	A0A388KWY8	A0A388KXE6	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.820
CBR_g18972	CBR_g32190	A0A388KWY8	A0A388JMY9	Uncharacterized protein.	Uncharacterized protein.	0.985
CBR_g18972	CBR_g50831	A0A388KWY8	A0A388M7J9	Uncharacterized protein.	Uncharacterized protein.	0.826
CBR_g18972	CBR_g5607	A0A388KWY8	A0A388JRK7	Uncharacterized protein.	PHTB1_C domain-containing protein.	0.991
CBR_g18972	CBR_g5686	A0A388KWY8	A0A388JRW0	Uncharacterized protein.	Uncharacterized protein.	0.714
CBR_g18972	CBR_g74496	A0A388KWY8	A0A388JJB3	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.714
CBR_g19121	CBR_g12706	A0A388KXE6	A0A388KSG5	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.813
CBR_g19121	CBR_g18972	A0A388KXE6	A0A388KWY8	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.820
CBR_g19121	CBR_g32190	A0A388KXE6	A0A388JMY9	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.811
CBR_g19121	CBR_g32516	A0A388KXE6	A0A388LGT8	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.813
CBR_g19121	CBR_g50450	A0A388KXE6	A0A388M746	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.813
CBR_g19121	CBR_g50831	A0A388KXE6	A0A388M7J9	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.905
CBR_g19121	CBR_g5607	A0A388KXE6	A0A388JRK7	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	PHTB1_C domain-containing protein.	0.797
CBR_g19121	CBR_g5686	A0A388KXE6	A0A388JRW0	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.791
CBR_g19121	CBR_g74496	A0A388KXE6	A0A388JJB3	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.791
CBR_g19121	CBR_g8649	A0A388KXE6	A0A388JS40	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.813
CBR_g32190	CBR_g18972	A0A388JMY9	A0A388KWY8	Uncharacterized protein.	Uncharacterized protein.	0.985

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Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.885

expected number of edges:

10

PPI enrichment p-value:

0.233

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046907

Intracellular transport

5 of 521

1.35

0.95

0.0054

GO:0006886

Intracellular protein transport

4 of 319

1.46

0.92

0.0092

GO:0015031

Protein transport

5 of 823

1.15

0.74

0.0124

GO:0006606

Protein import into nucleus

2 of 40

2.06

0.74

0.0427

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043227

Membrane-bounded organelle

11 of 7441

0.54

0.43

0.0011

GO:0043229

Intracellular organelle

11 of 7650

0.52

0.42

0.0011

GO:0005737

Cytoplasm

10 of 6797

0.53

0.41

0.0031

GO:0043231

Intracellular membrane-bounded organelle

10 of 6999

0.52

0.4

0.0033

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3521

LAG1, DNA binding, and Protein of unknown function DUF6699

2 of 5

2.97

1.61

0.0012

CL:2008

Mixed, incl. Exportin-1/5, and Zinc finger, RanBP2-type

2 of 5

2.97

1.61

0.0012

CL:1954

Nuclear pore

3 of 32

2.34

1.58

0.0011

CL:15982

Mostly uncharacterized, incl. Serine-type endopeptidase activity, and Multifunctional anion exchangers

3 of 145

1.68

1.17

0.0035

CL:16106

Mixed, incl. Multifunctional anion exchangers, and Tyrosine/serine-protein phosphatase IphP-type

2 of 34

2.14

1.1

0.0085

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-68875

Mitotic Prophase

3 of 53

2.12

1.62

0.00076

MAP-68886

M Phase

4 of 175

1.72

1.47

0.00070

MAP-2980766

Nuclear Envelope Breakdown

2 of 26

2.25

0.92

0.0198

MAP-69278

Cell Cycle, Mitotic

4 of 630

1.17

0.66

0.0253

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR040159

Suppressor of hairless-like

2 of 2

3.37

1.39

0.0032

IPR037095

RBP-J/Cbf11, DNA binding domain superfamily

2 of 2

3.37

1.39

0.0032

IPR036358

Beta-trefoil domain superfamily

2 of 2

3.37

1.39

0.0032

IPR015351

RBP-J/Cbf11/Cbf12, DNA binding

2 of 2

3.37

1.39

0.0032

IPR015350

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.39

0.0032

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01268

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.93

0.00034

SM01267

LAG1, DNA binding

2 of 2

3.37

1.93

0.00034

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