CBR_g23882 protein (Chara braunii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

CBR_g23882

Uncharacterized protein. (730 aa)

Predicted Functional Partners:

CBR_g41475

0.907

CBR_g41476

0.907

CBR_g51471

0.882

CBR_g29815

0.880

CBR_g29818

0.880

CBR_g29817

0.880

CBR_g40434

0.873

CBR_g46703

0.858

CBR_g3031

0.858

CBR_g26355

0.858

Your Current Organism:

Chara braunii

NCBI taxonomy Id: 69332
Other names: C. braunii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR_g23882	CBR_g26355	A0A388L5G1	A0A388L7Q9	Uncharacterized protein.	FAA_hydrolase domain-containing protein.	0.858
CBR_g23882	CBR_g29815	A0A388L5G1	A0A388LBG4	Uncharacterized protein.	Uncharacterized protein.	0.880
CBR_g23882	CBR_g29817	A0A388L5G1	A0A388LBH9	Uncharacterized protein.	Uncharacterized protein.	0.880
CBR_g23882	CBR_g29818	A0A388L5G1	A0A388LBH6	Uncharacterized protein.	Uncharacterized protein.	0.880
CBR_g23882	CBR_g3031	A0A388L5G1	A0A388KEQ9	Uncharacterized protein.	Uncharacterized protein.	0.858
CBR_g23882	CBR_g40434	A0A388L5G1	A0A388LTX3	Uncharacterized protein.	Uncharacterized protein.	0.873
CBR_g23882	CBR_g41475	A0A388L5G1	A0A388LVX4	Uncharacterized protein.	Uncharacterized protein.	0.907
CBR_g23882	CBR_g41476	A0A388L5G1	A0A388LW41	Uncharacterized protein.	Aldedh domain-containing protein.	0.907
CBR_g23882	CBR_g46703	A0A388L5G1	A0A388K401	Uncharacterized protein.	Uncharacterized protein.	0.858
CBR_g23882	CBR_g51471	A0A388L5G1	A0A388K6D0	Uncharacterized protein.	DHFR domain-containing protein.	0.882
CBR_g26355	CBR_g23882	A0A388L7Q9	A0A388L5G1	FAA_hydrolase domain-containing protein.	Uncharacterized protein.	0.858
CBR_g26355	CBR_g46703	A0A388L7Q9	A0A388K401	FAA_hydrolase domain-containing protein.	Uncharacterized protein.	0.885
CBR_g29815	CBR_g23882	A0A388LBG4	A0A388L5G1	Uncharacterized protein.	Uncharacterized protein.	0.880
CBR_g29815	CBR_g29817	A0A388LBG4	A0A388LBH9	Uncharacterized protein.	Uncharacterized protein.	0.853
CBR_g29815	CBR_g29818	A0A388LBG4	A0A388LBH6	Uncharacterized protein.	Uncharacterized protein.	0.977
CBR_g29815	CBR_g41475	A0A388LBG4	A0A388LVX4	Uncharacterized protein.	Uncharacterized protein.	0.549
CBR_g29815	CBR_g41476	A0A388LBG4	A0A388LW41	Uncharacterized protein.	Aldedh domain-containing protein.	0.549
CBR_g29815	CBR_g51471	A0A388LBG4	A0A388K6D0	Uncharacterized protein.	DHFR domain-containing protein.	0.590
CBR_g29817	CBR_g23882	A0A388LBH9	A0A388L5G1	Uncharacterized protein.	Uncharacterized protein.	0.880
CBR_g29817	CBR_g29815	A0A388LBH9	A0A388LBG4	Uncharacterized protein.	Uncharacterized protein.	0.853

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.429

expected number of edges:

16

PPI enrichment p-value:

0.000631

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044205

De novo UMP biosynthetic process

5 of 8

2.3

3.42

1.53e-07

GO:0009112

Nucleobase metabolic process

5 of 19

1.93

2.88

3.56e-07

GO:0046112

Nucleobase biosynthetic process

4 of 9

2.16

2.81

2.05e-06

GO:0009156

Ribonucleoside monophosphate biosynthetic process

6 of 33

1.77

2.75

1.53e-07

GO:0009084

Glutamine family amino acid biosynthetic process

5 of 23

1.85

2.68

6.36e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004088

Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

2 of 2

2.51

0.8

0.0355

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 4

2.21

0.79

0.0355

GO:0016597

Amino acid binding

2 of 3

2.33

0.79

0.0355

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1079

0.48

0.36

0.0075

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:768

De novo UMP biosynthetic process

5 of 8

2.3

3.72

3.27e-08

CL:715

Ribonucleoside monophosphate metabolic process, and IMP dehydrogenase activity

7 of 37

1.79

3.17

6.78e-09

CL:1254

Glutamine family amino acid biosynthetic process, and Glycine catabolic process

3 of 36

1.43

0.75

0.0249

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

tbi00250

Alanine, aspartate and glutamate metabolism

6 of 27

1.86

3.19

1.86e-08

tbi00240

Pyrimidine metabolism

6 of 27

1.86

3.19

1.86e-08

tbi01100

Metabolic pathways

11 of 670

0.72

4.15e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0665

Pyrimidine biosynthesis

5 of 10

2.21

3.52

5.72e-08

KW-0055

Arginine biosynthesis

3 of 9

2.03

1.69

0.00047

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02729

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain

2 of 2

2.51

0.85

0.0284

PF00185

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain

2 of 2

2.51

0.85

0.0284

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