CBR_g31959 protein (Chara braunii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

CBR_g31959

Uncharacterized protein. (746 aa)

Predicted Functional Partners:

CBR_g40841

0.679

CBR_g36926

0.643

GATA

0.620

CBR_g3545

0.620

CBR_g31867

0.620

CBR_g36483

0.620

CBR_g41054

0.620

CBR_g24327

0.613

CBR_g36336

0.587

CBR_g31512

0.570

Your Current Organism:

Chara braunii

NCBI taxonomy Id: 69332
Other names: C. braunii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR_g24327	CBR_g31959	A0A388JMF2	A0A388LG53	Uncharacterized protein.	Uncharacterized protein.	0.613
CBR_g31512	CBR_g31959	A0A388LF73	A0A388LG53	Uncharacterized protein.	Uncharacterized protein.	0.570
CBR_g31512	CBR_g40841	A0A388LF73	A0A388K259	Uncharacterized protein.	Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.	0.759
CBR_g31867	CBR_g31959	A0A388LFV9	A0A388LG53	Amidase domain-containing protein.	Uncharacterized protein.	0.620
CBR_g31959	CBR_g24327	A0A388LG53	A0A388JMF2	Uncharacterized protein.	Uncharacterized protein.	0.613
CBR_g31959	CBR_g31512	A0A388LG53	A0A388LF73	Uncharacterized protein.	Uncharacterized protein.	0.570
CBR_g31959	CBR_g31867	A0A388LG53	A0A388LFV9	Uncharacterized protein.	Amidase domain-containing protein.	0.620
CBR_g31959	CBR_g3545	A0A388LG53	A0A388KFN7	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.620
CBR_g31959	CBR_g36336	A0A388LG53	A0A388LKP8	Uncharacterized protein.	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.	0.587
CBR_g31959	CBR_g36483	A0A388LG53	A0A388LKZ6	Uncharacterized protein.	Amidase domain-containing protein.	0.620
CBR_g31959	CBR_g36926	A0A388LG53	A0A388JZF3	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.643
CBR_g31959	CBR_g40841	A0A388LG53	A0A388K259	Uncharacterized protein.	Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.	0.679
CBR_g31959	CBR_g41054	A0A388LG53	A0A388LV06	Uncharacterized protein.	Amidase domain-containing protein.	0.620
CBR_g31959	GATA	A0A388LG53	A0A388JSJ9	Uncharacterized protein.	Glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).	0.620
CBR_g3545	CBR_g31959	A0A388KFN7	A0A388LG53	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.620
CBR_g3545	CBR_g36336	A0A388KFN7	A0A388LKP8	TPR_REGION domain-containing protein.	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.	0.670
CBR_g36336	CBR_g31959	A0A388LKP8	A0A388LG53	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.	Uncharacterized protein.	0.587
CBR_g36336	CBR_g3545	A0A388LKP8	A0A388KFN7	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.	TPR_REGION domain-containing protein.	0.670
CBR_g36336	CBR_g36926	A0A388LKP8	A0A388JZF3	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.	TPR_REGION domain-containing protein.	0.670
CBR_g36336	CBR_g40841	A0A388LKP8	A0A388K259	Cellulose synthase; Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.	Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.	0.403

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Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.889

expected number of edges:

13

PPI enrichment p-value:

6.25e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009132

Nucleoside diphosphate metabolic process

7 of 58

2.45

6.02

4.55e-13

GO:0072528

Pyrimidine-containing compound biosynthetic process

5 of 28

2.62

4.81

5.53e-10

GO:0009142

Nucleoside triphosphate biosynthetic process

5 of 29

2.6

4.78

6.02e-10

GO:0009141

Nucleoside triphosphate metabolic process

6 of 73

2.28

4.67

1.67e-10

GO:0090407

Organophosphate biosynthetic process

9 of 281

1.87

4.45

4.55e-13

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016776

Phosphotransferase activity, phosphate group as acceptor

6 of 25

2.74

6.13

1.82e-12

GO:0019205

Nucleobase-containing compound kinase activity

6 of 29

2.68

6.04

2.01e-12

GO:0004550

Nucleoside diphosphate kinase activity

3 of 4

3.24

3.23

1.41e-06

GO:0004017

Adenylate kinase activity

3 of 4

3.24

3.23

1.41e-06

GO:0016772

Transferase activity, transferring phosphorus-containing groups

7 of 765

1.32

1.68

2.39e-06

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36277867

(2022) Cold-induced denaturation of muscle proteins in hairtail (Trichiurus lepturus) during storage: Physicochemical and label-free based proteomics analyses.

3 of 52

2.12

1.26

0.0040

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5678

Purine metabolism

9 of 40

2.72

9.69

3.16e-20

CL:5732

Mixed, incl. CTP metabolic process, and Adenylate kinase activity

7 of 13

3.09

9.1

9.18e-18

CL:5673

Mixed, incl. Purine metabolism, and Metabolism of nucleotides

10 of 157

2.17

7.13

1.42e-18

CL:5748

Adenylate kinase activity, and ATP cone domain

4 of 5

3.27

4.99

8.16e-10

CL:5734

Nucleoside diphosphate kinase, and Purine ribonucleoside bisphosphate metabolic process

2 of 5

2.97

1.63

0.0011

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pvm00230

Purine metabolism

9 of 76

2.44

8.5

2.35e-19

pvm00730

Thiamine metabolism

5 of 10

3.06

6.48

9.96e-13

pvm00240

Pyrimidine metabolism

5 of 36

2.51

5.02

1.24e-10

pvm00983

Drug metabolism - other enzymes

4 of 49

2.28

3.42

1.40e-07

pvm01100

Metabolic pathways

10 of 991

1.37

2.44

3.87e-12

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-499943

Interconversion of nucleotide di- and triphosphates

5 of 21

2.74

4.93

4.73e-10

MAP-15869

Metabolism of nucleotides

6 of 104

2.12

4.02

1.80e-09

MAP-1430728

Metabolism

7 of 2301

0.85

0.61

0.0055

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0418

Kinase

7 of 411

1.59

2.59

2.75e-08

KW-0547

Nucleotide-binding

6 of 685

1.31

1.48

2.31e-05

KW-0067

ATP-binding

5 of 552

1.32

1.33

0.00015

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13207

AAA domain

3 of 5

3.14

2.93

4.83e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR034907

Nucleoside diphosphate kinase-like domain

3 of 3

3.36

2.93

5.10e-06

IPR001564

Nucleoside diphosphate kinase

3 of 3

3.36

2.93

5.10e-06

IPR036850

Nucleoside diphosphate kinase-like domain superfamily

3 of 5

3.14

2.92

5.10e-06

IPR033690

Adenylate kinase, conserved site

3 of 5

3.14

2.92

5.10e-06

IPR000850

Adenylate kinase/UMP-CMP kinase

3 of 6

3.06

2.91

5.10e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00562

These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.

3 of 3

3.36

3.43

6.44e-07

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