STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D782_2575PFAM: Nitroreductase family. (183 aa)    
Predicted Functional Partners:
birA
birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.673
D782_2907
Hypothetical protein; PFAM: YcaO-like family; TIGRFAM: uncharacterized domain.
  
  
 0.579
D782_2576
PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type.
       0.566
D782_0237
ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter; ABC-2 family transporter protein.
  
  
 0.525
D782_2578
Nicotinamidase-like amidase; PFAM: Isochorismatase family.
  
    0.505
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.489
D782_2577
PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I.
       0.475
D782_4255
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.457
D782_3736
ABC-type polysaccharide/polyol phosphate export systems, permease component; PFAM: ABC-2 type transporter.
  
    0.445
D782_1838
acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme; Domain of unknown function (DUF4009).
 
 
   0.431
Your Current Organism:
Enterobacteriaceae bacterium strain
NCBI taxonomy Id: 693444
Other names: E. bacterium strain FGI 57, Enterobacteriaceae bacterium strain FGI 57
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