Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (366 aa)    
Predicted Functional Partners:
mrdB
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
   
 
 0.895
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
   
 
 0.857
rlmH
23S rRNA (pseudouridine-1915-N(3)-) methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
     
 0.820
rsfS
Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
 
 0.799
D782_3209
PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family.
  
  
 0.675
D782_2359
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: Domain of unknown function; 4Fe-4S dicluster domain; Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
   
   0.612
D782_3203
PFAM: Histidine phosphatase superfamily (branch 1); TIGRFAM: alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family.
       0.552
D782_0993
PFAM: Transglycosylase SLT domain; TIGRFAM: lytic murein transglycosylase B.
 
   
 0.551
mltG
Conserved hypothetical protein, YceG family; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.549
D782_3873
Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain.
 
   
 0.547
Your Current Organism:
Enterobacteriaceae bacterium strain
NCBI taxonomy Id: 693444
Other names: E. bacterium strain FGI 57, Enterobacteriaceae bacterium strain FGI 57
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