Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEA47901.1Protein of unknown function DUF107; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR001907: IPR002810; KEGG: fpl:Ferp_0768 protein of unknown function DUF107; PFAM: Nodulation efficiency, NfeD; Peptidase S14, ClpP; SPTR: Putative uncharacterized protein; PFAM: Clp protease; NfeD-like. (427 aa)    
Predicted Functional Partners:
AEA47535.1
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: apo:Arcpr_0231 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family.
 
  
 0.842
AEA47902.1
Domain of unknown function DUF357; COGs: COG1849 conserved hypothetical protein; InterPro IPR023140; KEGG: apo:Arcpr_0168 protein of unknown function DUF357; PFAM: Domain of unknown function DUF357; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF357).
       0.820
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
       0.773
AEA47904.1
COGs: COG1711 conserved hypothetical protein; KEGG: fpl:Ferp_1789 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
       0.773
rps27e
COGs: COG2051 Ribosomal protein S27E; HAMAP: Ribosomal protein S27e, archaea; InterPro IPR000592: IPR022959; KEGG: apo:Arcpr_1739 ribosomal protein S27E; PFAM: Ribosomal protein S27e; SPTR: 30S ribosomal protein S27e; PFAM: Ribosomal protein S27.
       0.741
AEA47503.1
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: fpl:Ferp_1342 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family.
 
  
 0.595
AEA47900.1
Site-specific DNA-methyltransferase (adenine-specific); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: afu:AF1715m type I restriction-modification enzyme, M subunit; PFAM: DNA methylase, adenine-specific; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system, M subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM).
       0.444
Your Current Organism:
Archaeoglobus veneficus
NCBI taxonomy Id: 693661
Other names: A. veneficus SNP6, Archaeoglobus veneficus DSM 11195, Archaeoglobus veneficus SNP6, Archaeoglobus veneficus str. SNP6, Archaeoglobus veneficus strain SNP6
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