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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fpg2_2Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family. (286 aa)    
Predicted Functional Partners:
fpg1
Formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 
0.899
fpg2_1
Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family.
  
  
 
0.873
polA_1
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.833
nei1_2
Endonuclease 8 1; Belongs to the FPG family.
  
  
 
0.710
ypcP
5'-3' exonuclease.
 
  
 0.613
ydaF_2
Putative ribosomal N-acetyltransferase YdaF.
 
     0.603
KJL41040.1
Putative DNA ligase-like protein.
  
     0.597
KJL42860.1
HhH-GPD superfamily base excision DNA repair protein.
  
  
 0.500
ykoU
Putative ATP-dependent DNA ligase YkoU.
  
     0.496
nei1_1
Endonuclease 8 1.
  
   
0.479
Your Current Organism:
Microbacterium trichothecenolyticum
NCBI taxonomy Id: 69370
Other names: ATCC 51475, Aureibacterium trichothecenolyticum, Aureobacterium trichothecenolyticum, CIP 103817, DSM 8608, IFO 15077, LMG 16696, LMG:16696, M. trichothecenolyticum, Microbacterium sp. BDR3P1B1, NBRC 15077
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