STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVADStage V sporulation protein AD. (338 aa)    
Predicted Functional Partners:
spoVAC
Stage V sporulation protein AC.
 
  
 0.964
spoVAE
Putative stage V sporulation protein AE.
 
  
 0.946
gpr
Putative germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.930
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.840
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.830
OBV_26720
Hypothetical protein.
 
  
 0.827
OBV_12200
Putative RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.814
spoVT
Transcriptional regulator spoVT; Protein synonym:stage V sporulation protein T.
  
   
 0.814
OBV_13700
Stage V sporulation protein AF.
  
  
 0.807
spoIIIAA
Stage III sporulation protein AA.
  
   
 0.801
Your Current Organism:
Oscillibacter valericigenes
NCBI taxonomy Id: 693746
Other names: O. valericigenes Sjm18-20, Oscillibacter valericigenes NBRC 101213, Oscillibacter valericigenes Sjm18-20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.