| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OBV_06480 | hisI/hisIE | OBV_06480 | OBV_42050 | Putative phosphoribosylformylglycinamidine synthase. | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.858 |
| OBV_06480 | pheA | OBV_06480 | OBV_37860 | Putative phosphoribosylformylglycinamidine synthase. | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | 0.685 |
| OBV_06480 | trpF | OBV_06480 | OBV_43880 | Putative phosphoribosylformylglycinamidine synthase. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.582 |
| hisI/hisIE | OBV_06480 | OBV_42050 | OBV_06480 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Putative phosphoribosylformylglycinamidine synthase. | 0.858 |
| hisI/hisIE | pheA | OBV_42050 | OBV_37860 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | 0.696 |
| hisI/hisIE | trpA | OBV_42050 | OBV_11230 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.723 |
| hisI/hisIE | trpB | OBV_42050 | OBV_11220 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.672 |
| hisI/hisIE | trpC | OBV_42050 | OBV_43870 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.704 |
| hisI/hisIE | trpD | OBV_42050 | OBV_43860 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.707 |
| hisI/hisIE | trpE | OBV_42050 | OBV_43840 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.782 |
| hisI/hisIE | trpF | OBV_42050 | OBV_43880 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.797 |
| hisI/hisIE | trpG | OBV_42050 | OBV_43850 | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Anthranilate synthase component II. | 0.587 |
| pheA | OBV_06480 | OBV_37860 | OBV_06480 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Putative phosphoribosylformylglycinamidine synthase. | 0.685 |
| pheA | hisI/hisIE | OBV_37860 | OBV_42050 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Histidine biosynthesis bifunctional protein HisIE; Bifunctional protein; protein synonym:phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.696 |
| pheA | trpA | OBV_37860 | OBV_11230 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.703 |
| pheA | trpB | OBV_37860 | OBV_11220 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.703 |
| pheA | trpC | OBV_37860 | OBV_43870 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.765 |
| pheA | trpD | OBV_37860 | OBV_43860 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.771 |
| pheA | trpE | OBV_37860 | OBV_43840 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.969 |
| pheA | trpF | OBV_37860 | OBV_43880 | Chorismate mutase/prephenate dehydratase; Bifunctional protein; protein synonym:P-protein. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.785 |