STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY26715.1COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003439:IPR003593; KEGG: dra:DR_2404 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, MsbA family; IMG reference gene:2504122969; PFAM: ABC transporter; ABC transporter transmembrane region. (605 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.614
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
   0.525
ADY26139.1
Heme-transporting ATPase; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ddr:Deide_08340 putative ABC transporter, ATP-binding component; PFAM: ABC transporter-like; PRIAM: Heme-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Putative ABC transporter, ATP-binding component; IMG reference gene:2504122359; PFAM: ABC transporter.
 
0.495
ADY26716.1
KEGG: ddr:Deide_17501 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504122970.
       0.489
ADY25490.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_0506 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ATPase component of ABC transporter, containing duplicated ATPase domains; IMG reference gene:2504121681; PFAM: ABC transporter.
  
 
 0.476
dnaJ-2
Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
  
 
 0.466
ADY26827.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dge:Dgeo_0381 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC-type transport system, ATPase component; IMG reference gene:2504123086; PFAM: ABC transporter.
 
0.457
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
   0.456
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.419
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.404
Your Current Organism:
Deinococcus proteolyticus
NCBI taxonomy Id: 693977
Other names: D. proteolyticus MRP, Deinococcus proteolyticus DSM 20540, Deinococcus proteolyticus MRP, Deinococcus proteolyticus str. MRP, Deinococcus proteolyticus strain MRP
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