| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADV42169.1 | ADV42171.1 | Bache_0139 | Bache_0141 | Metallophosphoesterase; InterPro IPR004843: IPR011230; KEGG: bth:BT_3885 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase. | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | 0.568 |
| ADV42169.1 | ispF | Bache_0139 | Bache_0140 | Metallophosphoesterase; InterPro IPR004843: IPR011230; KEGG: bth:BT_3885 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.663 |
| ADV42169.1 | rex | Bache_0139 | Bache_0142 | Metallophosphoesterase; InterPro IPR004843: IPR011230; KEGG: bth:BT_3885 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase. | CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.568 |
| ADV42171.1 | ADV42169.1 | Bache_0141 | Bache_0139 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Metallophosphoesterase; InterPro IPR004843: IPR011230; KEGG: bth:BT_3885 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase. | 0.568 |
| ADV42171.1 | ADV42173.1 | Bache_0141 | Bache_0143 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950: IPR017228; KEGG: bfr:BF4009 putative translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: Putative uncharacterized protein; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic. | 0.730 |
| ADV42171.1 | ADV42826.1 | Bache_0141 | Bache_0805 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017896: IPR001041: IPR004489; KEGG: bth:BT_3055 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. | 0.818 |
| ADV42171.1 | ADV42827.1 | Bache_0141 | Bache_0806 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: bth:BT_3054 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. | 0.840 |
| ADV42171.1 | ADV42828.1 | Bache_0141 | Bache_0807 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Succinate dehydrogenase subunit C; InterPro IPR011138; KEGG: bth:BT_3053 putative cytochrome b subunit; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. | 0.809 |
| ADV42171.1 | ADV43205.1 | Bache_0141 | Bache_1195 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.807 |
| ADV42171.1 | ADV43686.1 | Bache_0141 | Bache_1686 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | methylmalonyl-CoA epimerase; InterPro IPR017515: IPR004360; KEGG: bvu:BVU_2492 lactoyl gluthatione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. | 0.441 |
| ADV42171.1 | ADV45236.1 | Bache_0141 | Bache_3313 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: bvu:BVU_1961 citrate synthase; PFAM: Citrate synthase; SPTR: Putative uncharacterized protein; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.468 |
| ADV42171.1 | ispF | Bache_0141 | Bache_0140 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.779 |
| ADV42171.1 | rex | Bache_0141 | Bache_0142 | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.853 |
| ADV42173.1 | ADV42171.1 | Bache_0143 | Bache_0141 | COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950: IPR017228; KEGG: bfr:BF4009 putative translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: Putative uncharacterized protein; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic. | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | 0.730 |
| ADV42173.1 | ispF | Bache_0143 | Bache_0140 | COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950: IPR017228; KEGG: bfr:BF4009 putative translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: Putative uncharacterized protein; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.644 |
| ADV42173.1 | rex | Bache_0143 | Bache_0142 | COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950: IPR017228; KEGG: bfr:BF4009 putative translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: Putative uncharacterized protein; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic. | CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.684 |
| ADV42826.1 | ADV42171.1 | Bache_0805 | Bache_0141 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017896: IPR001041: IPR004489; KEGG: bth:BT_3055 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. | Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 putative hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Putative uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. | 0.818 |
| ADV42826.1 | ADV42827.1 | Bache_0805 | Bache_0806 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017896: IPR001041: IPR004489; KEGG: bth:BT_3055 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: bth:BT_3054 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. | 0.999 |
| ADV42826.1 | ADV42828.1 | Bache_0805 | Bache_0807 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017896: IPR001041: IPR004489; KEGG: bth:BT_3055 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. | Succinate dehydrogenase subunit C; InterPro IPR011138; KEGG: bth:BT_3053 putative cytochrome b subunit; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. | 0.997 |
| ADV42826.1 | ADV43205.1 | Bache_0805 | Bache_1195 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017896: IPR001041: IPR004489; KEGG: bth:BT_3055 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.988 |