STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV42249.1COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR020781: IPR003852; KEGG: bfs:BF0532 putative osmosensitive potassium transport sensor protein; PFAM: Osmosensitive K channel His kinase sensor; SPTR: Putative uncharacterized protein; PFAM: Osmosensitive K+ channel His kinase sensor domain; Universal stress protein family. (373 aa)    
Predicted Functional Partners:
kdpC
Potassium-transporting ATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.983
ADV42248.1
COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467: IPR000014: IPR003660: IPR004358: IPR 003661: IPR003594: IPR013767; KEGG: bfs:BF0533 putative two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: HAMP domain; Histidine kinase- [...]
 
 0.970
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.970
kdpA
Potassium-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.952
ADV42977.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: bfs:BF4150 putative two-component system sensor kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.918
ADV44510.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: bth:BT_1833 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.918
ADV42241.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bth:BT_1800 putative two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.667
ADV42054.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bfs:BF3635 two-component regulatory system, sensor kinase protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
      0.650
ADV44226.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: bfr:BF3214 putative two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.639
ADV42242.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661; KEGG: bth:BT_1801 two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: Two-component system sensor histidine kinase; PFAM: His Kinase A (phosphoacceptor) domain.
  
 
 0.593
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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