STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV42283.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR019734: IPR005467: IPR013026: IPR003661; KEGG: bth:BT_1598 putative two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; PFAM: His Kinase A (phosphoacceptor) domain. (677 aa)    
Predicted Functional Partners:
ADV44262.1
ATP-binding region ATPase domain protein; COGs: COG0326 Molecular chaperone HSP90 family; InterProIPR003594: IPR020576: IPR019805: IPR001404: IPR 020575; KEGG: bfs:BF2491 heat shock protein 90; PFAM: ATP-binding region ATPase domain protein; Heat shock protein Hsp90-like; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein.
  
 0.951
ADV42282.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bfr:BF0293 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 
0.928
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.898
ADV45206.1
Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: bth:BT_2034 two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain.
 
 
 
 0.878
ADV44475.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: bfs:BF2190 putative two component system histidine kinase/response regulator fusion protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
 
 
 0.805
ADV42484.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594: IPR001789: IPR018060: IPR004358: IPR 005467: IPR011110: IPR011123: IPR003661: IPR000005; KEGG: bvu:BVU_1267 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: ATP-binding region ATPase domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase [...]
 
 
 0.740
ADV44227.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR005467; KEGG: bth:BT_1598 putative two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: His Kinase A (phosphoacceptor) domain.
 
 
 
0.732
ADV43386.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060: IPR005467: IPR001789: IPR004358: IPR 011110: IPR003661: IPR003594: IPR000005; KEGG: bth:BT_2826 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain pro [...]
 
 
 0.730
ADV44446.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829: IPR001789: IPR001867; KEGG: bfs:BF2252 putative two component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.729
ADV42242.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661; KEGG: bth:BT_1801 two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: Two-component system sensor histidine kinase; PFAM: His Kinase A (phosphoacceptor) domain.
 
 
0.728
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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