STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV42329.1COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR000873; KEGG: bvu:BVU_0574 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme; PFAM: AMP-binding enzyme. (552 aa)    
Predicted Functional Partners:
ADV42328.1
Transcriptional regulator; InterPro IPR001387: IPR013096; KEGG: bfs:BF0477 putative regulatory protein; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain; Helix-turn-helix.
 
 0.991
ADV45236.1
COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: bvu:BVU_1961 citrate synthase; PFAM: Citrate synthase; SPTR: Putative uncharacterized protein; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.980
ADV45042.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017900: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017896; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidored [...]
  
 0.972
ADV42938.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: bvu:BVU_0986 2-oxoglutarate synthase subunit KorA; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Putative uncharacterized protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.938
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.935
ADV44806.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR005476; KEGG: bfs:BF1656 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: domain; Transketolase, C-terminal domain.
 
 
 0.931
ADV44808.1
Thiamine pyrophosphate TPP-binding domain-containing protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: bfs:BF1653 putative 2-oxoglutarate synthase subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
 
 0.931
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.927
ADV42383.1
COGs: COG0280 Phosphotransacetylase; InterPro IPR004614: IPR012147: IPR002505; KEGG: bfs:BF0423 putative phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
  
 
 0.922
ADV44196.1
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.920
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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