STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (254 aa)    
Predicted Functional Partners:
ADV43699.1
YbbR family protein; InterPro IPR012505; KEGG: bfs:BF1168 hypothetical protein; PFAM: YbbR family protein; SPTR: Putative uncharacterized protein; PFAM: YbbR-like protein.
 
  
 0.839
ADV42396.1
COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390: IPR000489; KEGG: bfs:BF0396 putative dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Putative uncharacterized protein; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
       0.804
ADV42394.1
Microcin-processing peptidase 2; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR006311: IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: Putative uncharacterized protein; PFAM: Putative modulator of DNA gyrase.
       0.767
ADV42393.1
Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: Putative uncharacterized protein; PFAM: Putative modulator of DNA gyrase.
       0.728
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
   
 0.702
mutS2
Smr protein/MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.586
ADV42397.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR019734: IPR003661: IPR003594: IPR004358: IPR 005467: IPR013026; KEGG: bth:BT_3645 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.527
ADV43043.1
7TM receptor with intracellular metal dependent phosphohydrolase; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR011621: IPR006674: IPR003607: IPR006675; KEGG: bfs:BF4031 putative transmembrane HD family protein; PFAM: metal-dependent phosphohydrolase 7TM intracellular region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Putative uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: 7TM-HD extracellular; HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterize [...]
 
  
 0.527
ADV42071.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005841: IPR016066: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: bfs:BF3668 putative phosphoglucomutase/phosphomannomutase family protein; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Putative uncharacterized protein; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta [...]
   
 
 0.518
ADV43972.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005841: IPR005844: IPR005845: IPR016066; KEGG: bvu:BVU_3804 putative phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: Putative uncharacterized protein; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomuta [...]
   
 
 0.518
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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