STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV42396.1COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390: IPR000489; KEGG: bfs:BF0396 putative dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Putative uncharacterized protein; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. (294 aa)    
Predicted Functional Partners:
ADV42774.1
COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: bfs:BF0071 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (HppK); PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrop [...]
 
 0.999
ADV43873.1
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR001645: IPR018109; KEGG: bfs:BF2850 putative folylpolyglutamate synthase; PFAM: Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: Putative uncharacterized protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
 
 0.997
ADV42035.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.990
ADV44409.1
KEGG: bth:BT_0744 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; SPTR: Putative uncharacterized protein; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
  
 
 0.976
folE
COGs: COG0302 GTP cyclohydrolase I; InterPro IPR001474: IPR018234: IPR020602; KEGG: bth:BT_3931 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
 0.935
ADV43238.1
KEGG: bvu:BVU_2234 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class IV.
  
 
 0.927
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.804
ADV42394.1
Microcin-processing peptidase 2; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR006311: IPR002510; KEGG: bth:BT_3648 putative modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: Putative uncharacterized protein; PFAM: Putative modulator of DNA gyrase.
     
 0.735
ADV42393.1
Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 putative modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: Putative uncharacterized protein; PFAM: Putative modulator of DNA gyrase.
     
 0.701
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
       0.643
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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