STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV42973.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003594: IPR004358; KEGG: bfs:BF4153 putative two-component regulator sensor histidine kinase transcriptional regulator; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (502 aa)    
Predicted Functional Partners:
ADV42974.1
COGs: COG0572 Uridine kinase; KEGG: bfr:BF4352 uridine kinase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family.
  
    0.743
ADV42975.1
Na/Pi-cotransporter II-related protein; COGs: COG1283 Na+/phosphate symporter; InterPro IPR003841: IPR008170: IPR004633; KEGG: bth:BT_2528 putative Na+-dependent phosphate transporter; PFAM: Na+/Picotransporter; PhoU family protein; SPTR: Putative uncharacterized protein; TIGRFAM: Na/Pi-cotransporter II-related protein; PFAM: PhoU domain; Na+/Pi-cotransporter; TIGRFAM: Na/Pi-cotransporter.
 
     0.729
ADV42242.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661; KEGG: bth:BT_1801 two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: Two-component system sensor histidine kinase; PFAM: His Kinase A (phosphoacceptor) domain.
 
 
 0.681
ADV45206.1
Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: bth:BT_2034 two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain.
 
 
 
 0.651
ADV42599.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR018060: IPR 004358: IPR005467: IPR011110: IPR011123: IPR000005; KEGG: bth:BT_3334 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; A [...]
  
 
 0.629
ADV44227.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR005467; KEGG: bth:BT_1598 putative two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: His Kinase A (phosphoacceptor) domain.
 
 
 
 0.626
ADV42054.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bfs:BF3635 two-component regulatory system, sensor kinase protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
 0.623
ADV44446.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829: IPR001789: IPR001867; KEGG: bfs:BF2252 putative two component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   0.618
ADV44521.1
KEGG: bfs:BF2565 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Autotransporter beta-domain.
  
     0.616
ADV44475.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: bfs:BF2190 putative two component system histidine kinase/response regulator fusion protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
  
   0.606
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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