STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV43012.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR002078: IPR001789: IPR002197: IPR003593: IPR 020441; KEGG: bth:BT_1469 two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigm [...] (500 aa)    
Predicted Functional Partners:
ADV43011.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterPro IPR005467: IPR003594: IPR004358; KEGG: bth:BT_1470 putative two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.924
ADV42964.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: bfr:BF4361 RNA polymerase sigma-54; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; SPTR: Putative uncharacterized protein; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
  
 0.802
ADV43014.1
Efflux transporter, RND family, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: bth:BT_1467 ABC transporter permease; PFAM: secretion protein HlyD family protein; SPTR: ABC transporter permease; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit.
 
   
 0.684
ADV44144.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterPro IPR003594: IPR005467: IPR000014: IPR004358; KEGG: bfr:BF2149 putative two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.632
ADV43016.1
Protein of unknown function DUF214; InterPro IPR003838; KEGG: bth:BT_1465 putative ABC transporter permease; PFAM: protein of unknown function DUF214; SPTR: Efflux ABC transporter, permease protein; PFAM: Predicted permease.
 
     0.610
ADV44916.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR000014: IPR003594: IPR003660: IPR013767: IPR 005467: IPR004358; KEGG: bth:BT_1528 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.559
ADV43013.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bth:BT_1468 putative outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein.
       0.486
ADV43141.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR008207: IPR003661: IPR 003594: IPR004358; KEGG: bth:BT_3805 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
  
 
 0.476
ADV43015.1
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: bth:BT_1466 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter.
       0.425
ADV44227.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR005467; KEGG: bth:BT_1598 putative two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: His Kinase A (phosphoacceptor) domain.
  
 
 0.424
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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