STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV43449.1COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: bth:BT_4258 putative 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; manually curated; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase. (178 aa)    
Predicted Functional Partners:
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.924
ADV43103.1
Formimidoyltetrahydrofolate cyclodeaminase; COGs: COG3404 Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: bfs:BF3967 putative formiminotransferase-cyclodeaminase; PFAM: Formiminotransferase-cyclodeaminase; SPTR: Putative uncharacterized protein; PFAM: Formiminotransferase-cyclodeaminase.
    
 0.918
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
 0.917
purT
Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
    
 0.907
ADV43101.1
COGs: COG3643 Glutamate formiminotransferase; InterPro IPR012886: IPR013802: IPR004227; KEGG: bvu:BVU_0334 formiminotransferase-cyclodeaminase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; PRIAM: Glutamate formimidoyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain, N-terminal subdomain; Formiminotransferase domain; TIGRFAM: glutamate formiminotransferase.
     
  0.900
ADV43448.1
COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140: IPR004013; KEGG: bfs:BF0879 putative histidinol-phosphatase; PFAM: PHP domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; Belongs to the PHP hydrolase family. HisK subfamily.
 
     0.869
ADV43450.1
C-terminal processing peptidase-3; COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR004447: IPR005151; KEGG: bfr:BF0963 carboxy-terminal processing protease precursor; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: carboxyl-terminal protease; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.
       0.853
ADV43451.1
CMP/dCMP deaminase zinc-binding protein; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR016473: IPR016192: IPR002125; KEGG: bfs:BF0882 putative deoxycytidylate deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Putative uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region.
  
    0.749
ADV43453.1
Peptidyl-dipeptidase Dcp; COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: bfs:BF0884 putative peptidyl-dipeptidase; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; PRIAM: Peptidyl-dipeptidase Dcp; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M3.
  
    0.730
ADV43452.1
KEGG: bth:BT_4261 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.726
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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