STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV43973.1NAD(+) diphosphatase; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375: IPR015376: IPR000086; KEGG: bth:BT_1544 NADH pyrophosphatase; PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; PRIAM: NAD(+) diphosphatase; SPTR: Putative uncharacterized protein; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain. (269 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 0.915
ADV44241.1
CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: bth:BT_0917 competence-damage inducible protein; PFAM: CinA domain protein; SPTR: Putative uncharacterized protein; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family.
    
 0.913
surE
5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
 
  0.911
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.911
cobB
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: bth:BT_2975 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: Putative uncharacterized protein; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.907
ADV42276.1
Metallophosphoesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR010916: IPR006146: IPR004843; KEGG: bfs:BF0515 secreted 5'-nucleotidase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
    
  0.905
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.904
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.903
ADV43962.1
COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638: IPR004393; KEGG: bth:BT_1560 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Putative uncharacterized protein; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
     
 0.903
ADV43974.1
KEGG: bth:BT_1424 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like, putative.
       0.823
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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