STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV44532.1C_GCAxxG_C_C family protein; InterPro IPR010181; KEGG: bfs:BF2583 hypothetical protein; PFAM: C_GCAxxG_C_C family protein; SPTR: Putative uncharacterized protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: Putative redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein. (155 aa)    
Predicted Functional Partners:
ADV44533.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR020847: IPR004808: IPR000097: IPR005135; KEGG: bth:BT_0630 exodeoxyribonuclease; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Putative uncharacterized protein; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
  
  
 0.835
ADV44534.1
Natural resistance-associated macrophage protein; COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; InterPro IPR001046; KEGG: bfs:BF2586 putative manganese transport-related membrane protein; PFAM: natural resistance-associated macrophage protein; SPTR: Putative uncharacterized protein; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters.
       0.811
ADV44535.1
KEGG: bth:BT_0628 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.728
ADV44536.1
Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: bth:BT_0627 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein HMPREF0969_00623; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family.
  
    0.676
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: bfr:BF2565 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Putative uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial.
     
 0.615
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.578
ADV44531.1
Protein of unknown function DUF2582; InterPro IPR019707; KEGG: bfs:BF2582 hypothetical protein; PFAM: Protein of unknown function DUF2582; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2582).
       0.490
ADV43910.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455; KEGG: bvu:BVU_2422 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; SMART: Rhodanese domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Rhodanese-like domain; [...]
  
 
 0.473
ADV44591.1
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140: IPR006139; KEGG: bth:BT_1207 glycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Glycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
     
 0.447
ADV44590.1
Recombination protein MgsA; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593: IPR003959; KEGG: bth:BT_1205 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA).
       0.430
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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